Article
How evolutionary systems biology will help understand adaptive landscapes and distributions of mutational effects.
Advances in experimental medicine and biology - 1 Jan 2012
Loewe Laurence
Abstract excerpt
Population genetics and ecology have been modeling biological systems quantitatively for over 8 decades and their results have contributed greatly to our understanding of the natural world and its evolution. Theories in these areas necessarily had to focus on comparisons of the contribution of different individuals to changes in the bigger picture at the expense of ignoring much of the complexity that exists...
Topics
- Adaptation, Physiological
- Animals
- Biological Evolution
- Circadian Clocks
- Environment
- Epistasis, Genetic
- Genetic Fitness
- Genetics, Population
- Genotype
- Humans
- Models, Genetic
- Mutation
- Plants
- Selection, Genetic
- Systems Biology
