Article
Autism risk gene MET variation and cortical thickness in typically developing children and adolescents.
Autism research : official journal of the International Society for Autism Research - 1 Dec 2012
Hedrick Alexis, Lee Yohan, Wallace Gregory L, Greenstein Deanna, Clasen Liv, Giedd Jay N, Raznahan Armin
Abstract excerpt
MET receptor tyrosine kinase (MET) has been proposed as a candidate risk gene for autism spectrum disorder (ASD) based on associations between MET polymorphisms and ASD diagnosis, as well as evidence from animal studies that MET protein may regulate early development of cortical regions implicated in the neurobiology of ASD. The relevance of differences in MET signaling for human cortical development remains...
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