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Article

Macrophage migration inhibitory factor and autism spectrum disorders.

Pediatrics - 1 Aug 2008

Grigorenko Elena L, Han Summer S, Yrigollen Carolyn M, Leng Lin, Mizue Yuka, Anderson George M, Mulder Erik J, de Bildt Annelies, Minderaa Ruud B, Volkmar Fred R, Chang Joseph T, Bucala Richard

Abstract excerpt

OBJECTIVE: Autistic spectrum disorders are childhood neurodevelopmental disorders characterized by social and communicative impairment and repetitive and stereotypical behavior. Macrophage migration inhibitory factor (MIF) is an upstream regulator of innate immunity that promotes monocyte/macrophage-activation responses by increasing the expression of Toll-like receptors and inhibiting activation-induced...

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Source

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Identifiers

PMID: 18676531
DOI: 10.1542/peds.2007-3604
PMCID: PMC3816765

Genes

MIF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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