Article
Association of TGF-beta1 codon 25 (G915C) polymorphism with hepatitis C virus infection.
Journal of medical virology - 1 Jan 2008
Pereira Fernanda Albuquerque, Pinheiro da Silva Naize Nara, Rodart Itatiana Ferreira, Carmo Theomira Mauadie Azevedo, Lemaire Denise Carneiro, Reis Mitermayer Galvão
Abstract excerpt
Cytokines play a key role in the regulation of immune responses. In hepatitis C virus infection (HCV), the production of abnormal cytokine levels appears to contribute to the progression of the disease, viral persistence, and affects response to therapy. Cytokine genes are polymorphic at specific sites, and certain polymorphisms located within coding/regulatory regions have been shown to affect the overall...
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