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Article

Transforming growth factor-beta1 gene polymorphisms are associated with disease progression in idiopathic pulmonary fibrosis.

American journal of respiratory and critical care medicine - 15 Aug 2003

Xaubet Antoni, Marin-Arguedas Alejandra, Lario Sergio, Ancochea Julio, Morell Ferran, Ruiz-Manzano Juan, Rodriguez-Becerra Eulogio, Rodriguez-Arias Jose M, Inigo Pablo, Sanz Sergi, Campistol Josep M, Mullol Joaquim, Picado Cesar

Abstract excerpt

Transforming growth factor-beta1 (TGF-beta1) is a cytokine that plays a key role in the development of idiopathic pulmonary fibrosis. There have been reports on the presence of two genetic polymorphisms in the DNA sequence encoding the leader sequence of the TGF-beta1 protein, located in codons 10 and 25. The objective of this study was to investigate the association between TGF-beta1 gene polymorphisms in codons...

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Identifiers

PMID: 12746254
DOI: 10.1164/rccm.200210-1165OC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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