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Article

Decreased expression of the GABAA receptor in fragile X syndrome.

Brain research - 22 Nov 2006

D'Hulst Charlotte, De Geest Natalie, Reeve Simon P, Van Dam Debby, De Deyn Peter P, Hassan Bassem A, Kooy R Frank

Abstract excerpt

After our initial discovery of under expression of the GABA(A) receptor delta subunit in a genome wide screening for differentially expressed mRNAs in brain of fragile X mice, a validated model for fragile X mental retardation syndrome, we analyzed expression of the 17 remaining subunits of the GABA(A) receptor using real-time PCR. We confirmed nearly 50% under expression of the delta subunit and found a...

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Share to Fragile X Mental Retardation Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17046729
DOI: 10.1016/j.brainres.2006.08.115

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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