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Article

Exaggerated behavioral phenotypes in Fmr1/Fxr2 double knockout mice reveal a functional genetic interaction between Fragile X-related proteins.

Human molecular genetics - 15 Jun 2006

Spencer Corinne M, Serysheva Ekaterina, Yuva-Paylor Lisa A, Oostra Ben A, Nelson David L, Paylor Richard

Abstract excerpt

Individuals affected by Fragile X syndrome (FXS) experience cognitive impairment, hyperactivity, attention deficits, social anxiety and autistic-like behaviors. FXS results from the loss of expression of the Fragile X mental retardation (FMR1) gene, whose protein product FMRP is thought to play a...

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Source

Identifiers

PMID: 16675531
DOI: 10.1093/hmg/ddl121

Genes

FMR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16675531-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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