Article
The effect of CD14-c159T genotypes on the cytokine response to endotoxin by peripheral blood mononuclear cells from asthmatic children.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology - 1 Sept 2006
Keskin Ozlem, Birben Esra, Saçkesen Cansin, Soyer Ozge U, Alyamaç Evrim, Karaaslan Cağatay, Tokol Nihan, Ercan Hülya, Kalayci Omer
Abstract excerpt
BACKGROUND: A C-T polymorphism at position 159 in the promoter of CD14 (C-159T) modulates the cellular response to endotoxin and significantly influences total IgE levels. The effect of this genetic variant on the cytokine response of the inflammatory cells is incompletely understood. OBJECTIVE:...
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