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Article

The effect of polymorphisms at the CD14 promoter and the TLR4 gene on asthma phenotypes in Turkish children with asthma.

Allergy - 1 Dec 2005

Saçkesen C, Karaaslan C, Keskin O, Tokol N, Tahan F, Civelek E, Soyer O U, Adalioglu G, Tuncer A, Birben E, Oner C, Kalayci O

Abstract excerpt

BACKGROUND: Endotoxin, with its potential to enhance type 1 immunity, is a significant player in the hygiene hypothesis. The combined effects of the genetic variants of various molecules in the endotoxin response pathway on asthma related phenotypes are largely unknown. OBJECTIVE: To investigate the effects of the genetic variants of CD14 and TLR4 genes on asthma phenotypes in a large number of asthmatic...

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Source

Identifiers

PMID: 16266379
DOI: 10.1111/j.1398-9995.2005.00874.x

Genes

TLR4

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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