Article
Suggestive evidence of association of C-159T functional polymorphism of the CD14 gene with atopic asthma in northern and northwestern Indian populations.
Immunogenetics - 1 Oct 2004
Sharma Mamta, Batra Jyotsna, Mabalirajan U, Goswami Sangeeta, Ganguly Dipyaman, Lahkar Brajen, Bhatia N K, Kumar Amrendra, Ghosh Balaram
Abstract excerpt
CD14 is a lipopolysaccharide receptor known to be an important modulator of Th1-Th2 response during early childhood. Genetic association studies of the CD14 gene with asthma and atopic disorders have shown positive as well as negative results in different ethnic populations. The aim of this study was to test for association of C-159T functional promoter polymorphism with atopic asthma and serum IgE levels in...
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