Article
The effect of CD14 C159T polymorphism on in vitro IgE synthesis and cytokine production by PBMC from children with asthma.
Allergy - 1 Jan 2011
Sackesen C, Birben E, Soyer O U, Sahiner U M, Yavuz T S, Civelek E, Karabulut E, Akdis M, Akdis C A, Kalayci O
Abstract excerpt
BACKGROUND: Even though the genotype at the promoter region of the CD14 molecule is known to affect the atopic phenotypes, the cellular and molecular basis of this association is largely unknown. OBJECTIVE: To investigate the effect of lipopolysaccharide (LPS) on IgE production and cytokine profile by peripheral blood mononuclear cells (PBMC) obtained from asthmatic children with the TT and the CC genotypes at...
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