Article
TNF-alpha (-308 G/A) and CD14 (-159T/C) polymorphisms in the bronchial responsiveness of Korean children with asthma.
The Journal of allergy and clinical immunology - 1 Feb 2007
Hong Soo-Jong, Kim Hyo-Bin, Kang Mi-Jin, Lee So-Yeon, Kim Ja-Hyung, Kim Bong-Seong, Jang Seong-Ok, Shin Hyung-Doo, Park Choon-Sik
Abstract excerpt
BACKGROUND: TNF-alpha is a pivotal proinflammatory cytokine increased in asthmatic airways. The TNF-alpha gene family might be linked to asthma or bronchial hyperresponsiveness (BHR), and TNF-alpha production might be modulated by CD14(+) cells. OBJECTIVE: We investigated the association between...
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