Article
The CD14 C-159T polymorphism is not associated with asthma or asthma severity in an Australian adult population.
Thorax - 1 Mar 2005
Kedda M-A, Lose F, Duffy D, Bell E, Thompson P J, Upham J
Abstract excerpt
BACKGROUND: CD14 functions as a multifunctional receptor for bacterial cell wall components including endotoxin and lipopolysaccharide and is likely to play a role in the polarisation of T lymphocytes into Th1 and Th2 subsets, thereby influencing the cytokine profile and subsequent IgE production in response to antigen/allergen contact in allergic phenotypes. A functional C-159T polymorphism has been described in...
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