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Article

159C>T CD14 genotype--functional effects on innate immune responses in term neonates.

Human immunology - 1 Jun 2008

Härtel Christoph, Rupp Jan, Hoegemann Anne, Bohler Annegret, Spiegler Juliane, von Otte Sören, Röder Kathrin, Schultz Christian, Göpel Wolfgang

Abstract excerpt

Given the susceptibility of newborns to infection and the potential harm of overwhelming proinflammatory immune responses, the impact of genetic variation in innate immune molecules is of increasing interest for risk stratification and prevention. We studied the functional relevance of the 159C>T CD14 single nucleotide polymorphism in cord blood samples of n=135 healthy term neonates by investigation of sCD14,...

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PMID: 18571004
DOI: 10.1016/j.humimm.2008.04.011

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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