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Article

Influence of C-159T SNP of the CD14 gene promoter on lung function in smokers.

Respiratory medicine - 1 Sept 2009

Zhou Haibo, Alexis Neil E, Almond Martha, Donohue James, LaForce Craig, Bromberg Philip A, Peden David B

Abstract excerpt

CD14, a co-receptor for endotoxin, plays a significant role in regulating the inflammatory response to this agent. The C-159T single nucleotide polymorphism (SNP) in the CD14 gene promoter is an important regulator of CD14 expression, with TT homozygotes having increased expression of CD14. This SNP has been linked to pathogenesis of asthma and with cardiovascular diseases in smokers. We hypothesize that CD14...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 19361972
DOI: 10.1016/j.rmed.2009.03.007
PMCID: PMC3178042

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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