Article
[Conservation of the MC domains in eukaryotic termination factor eRF3].
Genetika - 1 Jan 2007
Zhuravleva G A, Zemlianko O M, Le Goff C, Petrova A V, Philippe M, Inge-Vechtomov S G
Abstract excerpt
Eukaryotic translation termination employs two protein factors, eRF1 and eRF3. Proteins of the eRF3 family each consist of three domains. The N and M domains vary in different species, while the C domains are highly homologous. The MC domains of Homo sapiens eRF3a (hGSPT I), Xenopus laevis eRF3 (XSup35), and Mus musculus eRF3a (mGSPTI) and eRF3b (mGSPT2) were found to compensate for the sup35-21(ts)...
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