Influence of the gamma subunit and expression system on acetylcholine receptor gating.

doi:10.1016/0896-6273(90)90345-g

Back to search

Article

Influence of the gamma subunit and expression system on acetylcholine receptor gating.

Neuron - 1 Dec 1990

Lo D C, Pinkham J L, Stevens C F

Abstract excerpt

We have developed a partial kinetic theory for the gating of murine nicotinic acetylcholine receptors (AChRs) expressed in Xenopus oocytes and have used this theory to characterize the role of the gamma subunit in single-channel behavior. Permeation and gating were found to be largely unaffected...

Topics

Animals
Electric Conductivity
Electrophysiology
Female
Gene Expression
Ion Channel Gating
Ion Channels
Kinetics
Macromolecular Substances
Membrane Potentials
Mice
Mutation
Oocytes
Protein Conformation
RNA, Messenger
Receptors, Nicotinic
Structure-Activity Relationship
Transfection

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.