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Article

Structure of the gamma-less nicotinic acetylcholine receptor: learning from omission.

Molecular pharmacology - 1 Apr 1992

Charnet P, Labarca C, Lester H A

Abstract excerpt

The nicotinic acetylcholine receptor can be expressed in Xenopus oocytes by injection of in vitro synthesized RNA for the alpha, beta, gamma, and delta mouse muscle subunits. However, detectable responses can also be obtained by injection of alpha, beta, and delta subunit RNA only. The receptors expressed in this case (gamma-less receptors) share many of the properties of the normal receptor, including relaxation...

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PMID: 1373800

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