Article
Altered tyrosine 527 phosphorylation and mitotic activation of p60c-src.
Nature - 10 Jan 1991
Bagrodia S, Chackalaparampil I, Kmiecik T E, Shalloway D
Abstract excerpt
The tyrosine kinasee activity of p60c-src, the protein product of the c-src gene, increases during mitosis; this may be important in initiating at least some of the cellular changes that occur during this phase of the cell cycle. Although there is evidence that p60c-src is phosphorylated at sever...
Topics
- Animals
- Cell Line
- Enzyme Activation
- Mice
- Mitosis
- Mutation
- Peptide Mapping
- Phosphorylation
- Phosphotyrosine
- Proto-Oncogene Proteins pp60(c-src)
- Structure-Activity Relationship
- Tyrosine