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Article

Role of different pathways of the complement cascade in experimental bullous pemphigoid.

The Journal of clinical investigation - 1 Nov 2006

Nelson Kelly C, Zhao Minglang, Schroeder Pamela R, Li Ning, Wetsel Rick A, Diaz Luis A, Liu Zhi

Abstract excerpt

Bullous pemphigoid (BP) is an autoimmune subepidermal blistering disease associated with autoantibodies directed against the hemidesmosomal proteins BP180 and BP230 and inflammation. Passive transfer of antibodies to the murine BP180 (mBP180) induces a skin disease that closely resembles human BP. In the present study, we defined the roles of the different complement activation pathways in this model system. Mice...

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Share to Collagen Type XVII

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Complement C1q

Share to Complement C4

Share to Complement Factor B

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Share to Pemphigoid, Bullous

Source

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Identifiers

PMID: 17024247
DOI: 10.1172/JCI17891
PMCID: PMC1590266

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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