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The relevance of complement in pemphigoid diseases: A critical appraisal

16 Aug 2022

Abstract excerpt

Pemphigoid diseases are autoimmune chronic inflammatory skin diseases, which are characterized by blistering of the skin and/or mucous membranes, and circulating and tissue-bound autoantibodies. The well-established pathomechanisms comprise autoantibodies targeting various structural proteins located at the dermal-epidermal junction, leading to complement factor binding and activation. Several effector cells are...

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PMID: 36059476
DOI: 10.3389/fimmu.2022.973702

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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