Article
Myeloid-related proteins-8 and -14 are expressed but dispensable in the pathogenesis of experimental epidermolysis bullosa acquisita and bullous pemphigoid.
Journal of dermatological science - 1 Mar 2016
Akbarzadeh Reza, Yu Xinhua, Vogl Thomas, Ludwig Ralf J, Schmidt Enno, Zillikens Detlef, Petersen Frank
Abstract excerpt
BACKGROUND: Myeloid-related protein-8 (MRP-8) and its heterodimeric partner, MRP-14 belong to the group of danger-associated molecular patterns (DAMPs) and are associated with numerous chronic human disorders. However, their functional role in autoimmunity remains largely unclear. OBJECTIVE: Here, we examined the involvement of MRP-8/-14 in two difficult-to-treat autoimmune blistering diseases, epidermolysis...
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