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Article

Characterization of the human intestinal CD98 promoter and its regulation by interferon-gamma.

American journal of physiology. Gastrointestinal and liver physiology - 1 Feb 2007

Yan Yutao, Dalmasso Guillaume, Sitaraman Shanthi, Merlin Didier

Abstract excerpt

Growing evidence that epithelial CD98 plays an important role in intestinal inflammation focused our interest to investigate the transcriptional regulation of CD98. Our mouse-based in vivo and in vitro experiments revealed that epithelial colonic CD98 mRNA expression was transcriptionally increased in intestinal inflammation. We then isolated and characterized a 5'-flanking fragment containing the promoter region...

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Identifiers

PMID: 17023546
DOI: 10.1152/ajpgi.00385.2006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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