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Article

Transcription Factor SP2 Enhanced the Expression of Cd14 in Colitis-Susceptible C3H/HeJBir.

PloS one - 1 Jan 2016

Zschemisch Nils-Holger, Brüsch Inga, Hambusch Anne-Sophie, Bleich André

Abstract excerpt

Genetic analysis in the IL10-deficient mouse model revealed a modifier locus of experimental inflammatory bowel disease (IBD) on chromosome 18, with the allele of the strain C3H/HeJBir (C3Bir) conferring resistance and the allele of C57BL/6J (B6) conferring susceptibility. Differential Cd14 expression was associated with this background specific susceptibility to intestinal inflammation. Polymorphisms of the Cd14...

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Share to Alleles
Share to Cell Line
Share to Colitis, Ulcerative

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to STAT1 gene

Share to Lipopolysaccharide Receptors

Share to Promoter Regions, Genetic

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Source

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Identifiers

PMID: 27191968
DOI: 10.1371/journal.pone.0155821
PMCID: PMC4871554

Genes

CDX1
STAT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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