Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Regulation of S100A2 expression by TGF-β-induced MEK/ERK signalling and its role in cell migration/invasion

3 Jul 2012

Abstract excerpt

S100A2, an EF hand calcium-binding protein, is a potential biomarker in several cancers and is also a TGF-β (transforming growth factor-β)-regulated gene in melanoma and lung cancer cells. However, the mechanism of S100A2 regulation by TGF-β and its significance in cancer progression remains largely unknown. In the present study we report the mechanism of S100A2 regulation by TGF-β and its possible role in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Clusterin in disease pathology
Share to S100 Proteins and Annexins
Share to TGF-β signaling in diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22747445
DOI: 10.1042/bj20120014

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Regulation of S100A2 expression by TGF-β-induced MEK/ERK signalling and its role in cell migration/invasionPMID 22747445Read ↗

The p53-S100A2 Positive Feedback Loop Negatively Regulates Epithelialization in Cutaneous Wound HealingSemantic proximity Read ↗

Downregulation of S100A2 alleviates pulmonary fibrosis through inhibiting wnt/β-catenin signaling pathwaySemantic proximity Read ↗

Proteomics of Smad4 regulated transforming growth factor-beta signalling in colon cancer cellsSemantic proximity Read ↗

Activation of NF‐κB by extracellular S100A4: Analysis of signal transduction mechanisms and identification of target genesSemantic proximity Read ↗

The Role of the S100 Protein Family in GliomaSemantic proximity Read ↗

The Ca2+-binding Proteins S100A8 and S100A9 Are Encoded by Novel Injury-regulated GenesSemantic proximity Read ↗

Expression profile and functional role of S100A14 in human cancerSemantic proximity Read ↗

TGFβ1‐induced beta‐site APP‐cleaving enzyme 2 upregulation promotes tumorigenesis through the NF‐κB signalling pathway in human gliomasSemantic proximity Read ↗

Role of areca nut induced JNK/ATF2/Jun axis in the activation of TGF-β pathway in precancerous Oral Submucous FibrosisSemantic proximity Read ↗

Transcriptional activation of the tumor suppressor and differentiation gene S100A2 by a novel p63-binding site.Semantic proximity Read ↗

Cell-specific Induction of Distinct Oncogenes of the Jun Family Is Responsible for Differential Regulation of Collagenase Gene Expression by Transforming Growth Factor-β in Fibroblasts and KeratinocytesSemantic proximity Read ↗

The S100A7-c-Jun activation domain binding protein 1 pathway enhances prosurvival pathways in breast cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.