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Article

Transcription factors C/EBP-beta and -delta regulate IL-6 production in IL-1beta-stimulated human enterocytes.

Journal of cellular physiology - 1 Jul 2002

Hungness Eric S, Luo Guang-Ju, Pritts Timothy A, Sun Xiaoyan, Robb Bruce W, Hershko Dan, Hasselgren Per-Olof

Abstract excerpt

In recent studies, treatment with IL-1beta of cultured Caco-2 cells, a human intestinal epithelial cell line, resulted in transcriptional upregulation of IL-6 production. The role of C/EBP-beta and -delta in enterocyte IL-6 production is not known. Stimulation with IL-1beta of Caco-2 cells transiently transfected with a luciferase reporter plasmid containing a wild-type IL-6 promoter resulted in an approximately...

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Identifiers

PMID: 12115737
DOI: 10.1002/jcp.10116

Genes

EBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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