Article
[The role of genetic factors on the link between stress and alcohol use: the example of CRH-R1].
Presse medicale (Paris, France : 1983) - 1 Jan 2012
Le Strat Yann, Dubertret Caroline
Abstract excerpt
There are no straightforward relationships between stressful life events, genetic factors and alcohol use. Human and animal-based studies suggest that stress exposure increase the risk of alcohol use and relapse among alcohol-dependent subjects. The physiological mechanisms underlying these links remain unknown. Alcohol dependence heritability ranges between 50% and 70%. Of the potentially involved genes, CRH-R1...
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