Back to search

Article

Predator odor stress produces sex- and subpopulation-specific increases in alcohol drinking, anxiety-like behavior, and lateral hypothalamic <i>crh</i> expression

2025-03-20

Abstract excerpt

Traumatic stress leads to maladaptive avoidance behaviors and alcohol misuse in some people. In rats, predator odor (“traumatic”) stress produces persistent avoidance of stress-paired contexts and escalated alcohol self-administration in some animals (Avoiders), but not others (Non-Avoiders). This mirrors the individual differences in stress responsivity and alcohol misuse seen in humans. Here, we used a quinine-a...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
6c20d7c0-9e16-5896-b413-d89f7b587b77
DOI
10.1101/2025.03.20.644324
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Predator odor stress produces sex- and subpopulation-specific increases in alcohol drinking, anxiety-like behavior, and lateral hypothalamic <i>crh</i> expressionDOI 10.1101/2025.03.20.644324
Sex and context differences in the effects of trauma on comorbid alcohol use and post-traumatic stress phenotypes in actively drinking rats.Semantic proximity
The synthetically produced predator odor 2,5-dihydro-2,4,5-trimethylthiazoline increases alcohol self-administration and alters basolateral amygdala response to alcohol in ratsSemantic proximity
Predator odor (TMT) exposure potentiates interoceptive sensitivity to alcohol and increases GABAergic gene expression in the anterior insular cortex and nucleus accumbens in male ratsSemantic proximity
Differential c-Fos Response in Neurocircuits Activated by Repeated Predator Stress in Male and Female C57BL/6J Mice with Stress Sensitive or Resilient Alcohol Intake Phenotypes.Semantic proximity
Chronic Alcohol Consumption Alters Home-Cage Behaviors and Responses to Ethologically Relevant Predator Tasks in MiceSemantic proximity
Anxiety response and restraint-induced stress differentially affect ethanol intake in female adolescent rats.Semantic proximity
Sex differences in binge alcohol drinking and the behavioral consequences of protracted abstinence in C57BL/6J miceSemantic proximity
Fear-conditioning to unpredictable threats reveals sex differences in rat fear-potentiated startle (FPS)Semantic proximity
Early life stress modulates behavioral sensitivity to alcohol and promotes escalation of alcohol drinkingSemantic proximity
A novel approach to PTSD modeling in rats reveals alternating patterns of limbic activity in different types of stress reaction.Semantic proximity
Variation at the rat Crhr1 locus and sensitivity to relapse into alcohol seeking induced by environmental stress.Semantic proximity
Embryonic alcohol exposure leading to social avoidance and altered anxiety responses in adult zebrafishSemantic proximity
Select a neighboring publication to make it the new centre.