Article
Characterization of in vivo-activated T cell clones from peripheral blood of multiple sclerosis patients.
Clinical immunology and immunopathology - 1 Jan 1991
Ofosu-Appiah W, Mokhtarian F, Miller A, Grob D
Abstract excerpt
In vivo-activated interleukin-2 responsive T cell clones were generated from peripheral blood (PBL) of multiple sclerosis patients (MS) and normal subjects (N) by limiting dilution analysis. The frequency with which interleukin-2 responsive cells were cloned from PBL was higher in MS than N. CD8 was the predominant phenotype expressed by both MS (85%) and N (89%) clones. Seven clones from four MS patients but...
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