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Article

Blood B Cell and Regulatory Subset Content in Multiple Sclerosis Patients

1 Jan 2015

Abstract excerpt

OBJECTIVE: B cell targeted therapies have been effective in slowing multiple sclerosis (MS) disease progression suggesting a direct causal link for this lymphoid subset. A small subset of B cells with regulative properties (Bregs) exists in peripheral blood, and induction of Bregs ameliorates experimental autoimmune encephalomyelitis (EAE), the murine model for MS. Therefore the frequency of B cell subsets and...

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PMID: 26137596
DOI: 10.4172/2376-0389.1000139

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