Article
Cytokine secretion profile of myelin basic protein-specific T cells in multiple sclerosis.
Multiple sclerosis (Houndmills, Basingstoke, England) - 1 Apr 2000
Rohowsky-Kochan C, Molinaro D, Cook S D
Abstract excerpt
Multiple sclerosis (MS) is a demyelinating disease of the central nervous system with a presumed autoimmune pathogenesis involving autoantigen-specific CD4+ T cells and cytokines. A similar frequency of T cells responding to myelin basic protein (MBP), a putative target in MS, has been observed in MS patients and controls. To dissect the differences between MBP-specific T cells in patients and controls, we have...
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