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Article

Experimental and computational assessment of conditionally essential genes in Escherichia coli.

Journal of bacteriology - 1 Dec 2006

Joyce Andrew R, Reed Jennifer L, White Aprilfawn, Edwards Robert, Osterman Andrei, Baba Tomoya, Mori Hirotada, Lesely Scott A, Palsson Bernhard Ø, Agarwalla Sanjay

Abstract excerpt

Genome-wide gene essentiality data sets are becoming available for Escherichia coli, but these data sets have yet to be analyzed in the context of a genome scale model. Here, we present an integrative model-driven analysis of the Keio E. coli mutant collection screened in this study on glycerol-supplemented minimal medium. Out of 3,888 single-deletion mutants tested, 119 mutants were unable to grow on glycerol...

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Identifiers

PMID: 17012394
DOI: 10.1128/JB.00740-06
PMCID: PMC1698209

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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