Article
Profiles of gene polymorphisms in cytokines and Toll-like receptors with higher risk for gastric cancer.
Digestive diseases and sciences - 1 Apr 2013
de Oliveira Juliana Garcia, Rossi Ana Flávia Teixeira, Nizato Daniela Manchini, Miyasaki Kenji, Silva Ana Elizabete
Abstract excerpt
BACKGROUND: Chronic inflammation and gastric carcinogenesis show a close association, so gene polymorphisms that modify the intensity of the inflammatory response may contribute to variations in gastric cancer risk. AIMS: The purpose of this study was to investigate the combined effect of the pro- and anti-inflammatory cytokines and toll-like receptors polymorphisms on the chronic gastritis and gastric cancer...
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