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Article

Host polymorphisms of immune regulatory genes as risk factors for gastric cancer.

Minerva gastroenterologica e dietologica - 1 Dec 2009

Wex T, Bornschein J, Malfertheiner P

Abstract excerpt

The infection of the stomach with the gram-negative bacterium Helicobacter pylori is the main risk factor for the development of gastric cancer (GC). This led to the classification of this germ as "definite carcinogen" by the World Health Organization in 1994. The current model of gastric carcinogenesis is based on the interaction of multiple risk factors including virulence factors of the bacterium (e.g. CagA,...

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PMID: 19942825

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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