Article
Association of interleukin-1beta gene polymorphisms with precancerous gastric lesions in African Americans and Caucasians.
The American journal of gastroenterology - 1 Jan 2006
Zabaleta Jovanny, Camargo M Constanza, Piazuelo M Blanca, Fontham Elizabeth, Schneider Barbara G, Sicinschi Liviu A, Ferrante William, Balart Luis, Correa Pelayo, Ochoa Augusto C
Abstract excerpt
OBJECTIVE: Interleukin-1beta plays an important role in inflammation and gastric physiology. Polymorphisms of the IL1B gene have been associated with gastric atrophy and increased cancer risk, especially in Helicobacter pylori-infected subjects. The aim of this study was to evaluate the relationship between IL1B and IL1 receptor antagonist gene polymorphisms and the risk of multifocal atrophic gastritis in...
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