Article
Decreased risk for myocardial infarction and lower tumor necrosis factor-alpha levels in carriers of variants of the PDCD1 gene.
Human immunology - 1 Sept 2006
Bennet Anna M, Alarcón-Riquelme Marta, Wiman Björn, de Faire Ulf, Prokunina-Olsson Ludmila
Abstract excerpt
Increasing interest has been directed toward the inflammatory mechanisms involved in the pathogenesis of myocardial infarction (MI). In the search for genetic mechanisms underlying these inflammatory components, we studied variants of programmed cell death-1 (PDCD1), an immunoinhibitory receptor that inhibits lymphocyte activation and cytokine production, previously shown to be associated with several autoimmune...
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