Article
Effect of TNF-α and IL-1β genetic variants on the development of myocardial infarction in Turkish population.
Molecular biology reports - 1 Nov 2011
Zeybek Umit, Toptas Bahar, Karaali Zeynep Ermis, Kendir Mehmet, Cakmakoglu Bedia
Abstract excerpt
Tumor necrosis factor-alpha (TNF-α) and interleukin 1 beta (IL-1β) genetic variants which resulting in TNF-α and IL-1 overproduction may increase susceptibility to autoimmune diseases such as atherosclerosis. We have studied the association of TNF-α G308A and IL-1β (+3953) C/T polymorphism with myocardial infarction in Turkish population. 143 patients with myocardial infarction and 213 age-matched healthy...
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