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Article

Acute myocardial infarction and proinflammatory gene variants.

Annals of the New York Academy of Sciences - 1 Nov 2007

Licastro Federico, Chiapelli Martina, Caldarera Claudio Marcello, Caruso Calogero, Lio Domenico, Corder Elizabeth H

Abstract excerpt

We identified four genetic risk sets for acute myocardial infarction (AMI) from information on functional gene variants that favor inflammation or modulate cholesterol metabolism: IL6 -174 G/C, TNF -308 G/A, IL10 -1082 G/A, SERPINA3 -51 G/T, IFNG +874 T/A, HMGCR -911 C/A, and APOE epsilon2/3/4; 316 patients and 461 healthy subjects, all Italian. Putative risk alleles are shown underlined. The sets were identified...

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Identifiers

PMID: 18056971
DOI: 10.1196/annals.1404.004

Genes

TNF
HMGCR
IFNG
SERPINA3
APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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