Article
Identification of novel polymorphisms in the nuclear protein genes and their relationship with human sperm protamine deficiency and severe male infertility.
Fertility and sterility - 1 Nov 2006
Aoki Vincent W, Christensen Greg L, Atkins John F, Carrell Douglas T
Abstract excerpt
OBJECTIVE: To screen populations of fertile men, severely infertile men, and infertility patients with aberrations in the protamine-1-to-protamine-2 ratio (P1/P2) for clinically relevant alterations in the P1, P2, transition protein 1 (TP1), and transition protein 2 (TP2) genes. DESIGN: Prospective case-control study. SETTING: University-based infertility clinic. PATIENT(S): Ninety-six fertile men, 96 severely...
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