Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of genetic variation in the 5' and 3' non-coding regions of the protamine genes in patients with protamine deregulation.

Archives of andrology - 1 Jan 2000

Hammoud Sue, Emery Benjamin R, Aoki Vincent W, Carrell Douglas T

Abstract excerpt

Deregulation of sperm nuclear protamine ratio (P1/P2) has been shown to correlate with male factor infertility in humans, but the cause of this abnormal protein expression has yet to be identified. Recent studies have shown that there is little genetic variability in the coding regions of either of the protamine gene sequences. However, these studies did not investigate the 5' or 3' non-coding regions of these...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3' Untranslated Regions
Share to 5' Untranslated Regions

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Base Sequence

Share to DNA Primers

Share to Genetic Variation

Share to Polymorphism, Single Nucleotide

Share to Protamines

Source

Identifiers

PMID: 18309899
DOI: 10.1080/01485010701569890

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of genetic variation in the 5' and 3' non-coding regions of the protamine genes in patients with protamine deregulation.PMID 18309899Read ↗

Mutations in the protamine locus: association with spermatogenic failure?Semantic proximity Read ↗

The aetiology of sperm protamine abnormalities and their potential impact on the sperm epigenome.Semantic proximity Read ↗

Single nucleotide polymorphisms in the protamine-1 and -2 genes of fertile and infertile human male populations.Semantic proximity Read ↗

Identification of novel polymorphisms in the nuclear protein genes and their relationship with human sperm protamine deficiency and severe male infertility.Semantic proximity Read ↗

Protamine alterations in human spermatozoa.Semantic proximity Read ↗

Polymorphisms, haplotypes and mutations in the protamine 1 and 2 genesSemantic proximity Read ↗

An SNP in protamine 1: a possible genetic cause of male infertility?Semantic proximity Read ↗

Identification and evaluation of a novel sperm protamine abnormality in a population of infertile malesSemantic proximity Read ↗

A common protamine 1 promoter polymorphism (-190 C->A) correlates with abnormal sperm morphology and increased protamine P1/P2 ratio in infertile patients.Semantic proximity Read ↗

Protamine-1 and -2 polymorphisms and gene expression in male infertility: an Italian study.Semantic proximity Read ↗

Altered protamine expression and diminished spermatogenesis: what is the link?Semantic proximity Read ↗

Unexplained recurrent miscarriages are associated with an aberrant sperm protamine mRNA contentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.