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Article

Epigenetic boundaries of tumour suppressor gene promoters: the CTCF connection and its role in carcinogenesis.

Journal of cellular and molecular medicine - 1 Jan 2000

Recillas-Targa Felix, De La Rosa-Velázquez Inti A, Soto-Reyes Ernesto, Benítez-Bribiesca Luis

Abstract excerpt

Genetic and epigenetic regulations are essential mechanisms that ensure proper early and subsequent mammalian programming of diverse cellular processes. These mechanisms affect transcriptional regulation, stem cell determination and cell cycle control, including senescence and aging. It is not surprising that perturbation of the exquisite balance between genetic and epigenetic regulation can lead to diverse...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 16989720
DOI: 10.1111/j.1582-4934.2006.tb00420.x
PMCID: PMC3933142

Genes

CTCF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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CTCF binding site classes exhibit distinct evolutionary, genomic, epigenomic and transcriptomic featuresSemantic proximity Read ↗

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