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Analyzing the impact of CFP1 mutational landscape on epigenetic signaling.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Aug 2021

Yang Yidai, Yang Yaqing, Chan Kin, Couture Jean-Francois

Abstract excerpt

CXXC Zinc finger protein 1 (CFP1) is a multitasking protein playing essential roles during various developmental processes. Its ability to interact with several proteins contribute to several epigenetic events. Here, we review CFP1's functions and its impact on DNA methylation and the post-translational modification of histone proteins such as lysine acetylation and methylation. We will also discuss the potential...

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PMID: 34320252
DOI: 10.1096/fj.202100427R

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