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Article

KRAS, p53 and BRAF gene mutations and aneuploidy in sporadic colorectal cancer progression.

Cellular oncology : the official journal of the International Society for Cellular Oncology - 1 Jan 2006

Calistri Daniele, Rengucci Claudia, Seymour Ian, Leonardi Elena, Truini Mauro, Malacarne Davide, Castagnola Patrizio, Giaretti Walter

Abstract excerpt

BACKGROUND: The origin and mechanisms of chromosomal instability are still widely unknown. We previously investigated a limited number of human sporadic colorectal cancers (CRCs) and observed a statistically different occurrence of KRAS and p53 mutations among predetermined subgroups of tumors with different degrees of DNA aneuploidy. The aim of the present study was to further verify these observations by...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 16988471
DOI: 10.1155/2006/465050
PMCID: PMC4615153

Genes

KRAS
BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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