Genetic pathways and genome-wide determinants of clinical outcome in colorectal cancer.

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Article

Genetic pathways and genome-wide determinants of clinical outcome in colorectal cancer.

Cancer research - 1 Nov 2003

Risques Rosa-Ana, Moreno Victor, Ribas Maria, Marcuello Eugenio, Capellà Gabriel, Peinado Miguel A

Abstract excerpt

Various studies have suggested the existence of different pathways of tumor progression in colorectal cancer that associate with specific molecular, chromosomal, and clinicopathological features. We hypothesize that a comprehensive analysis of cumulated genomic damage in colorectal cancers would aid the characterization of different tumor progression pathways and identify the factors determining clinical outcome...

Topics

Adult
Aged
Aged, 80 and over
Aneuploidy
Colorectal Neoplasms
DNA Fingerprinting
Diploidy
Disease Progression
Female
Genome, Human
Humans
Male
Middle Aged
Mutation
Neoplasm Staging
Polymerase Chain Reaction
Prognosis

Source

Open in PubMed

Identifiers

PMID: 14612515

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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