Article
Genetic pathways and genome-wide determinants of clinical outcome in colorectal cancer.
Cancer research - 1 Nov 2003
Risques Rosa-Ana, Moreno Victor, Ribas Maria, Marcuello Eugenio, Capellà Gabriel, Peinado Miguel A
Abstract excerpt
Various studies have suggested the existence of different pathways of tumor progression in colorectal cancer that associate with specific molecular, chromosomal, and clinicopathological features. We hypothesize that a comprehensive analysis of cumulated genomic damage in colorectal cancers would aid the characterization of different tumor progression pathways and identify the factors determining clinical outcome...
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