Article
Chromosomal instability, aneuploidy, and gene mutations in human sporadic colorectal adenomas.
Cellular oncology : the official journal of the International Society for Cellular Oncology - 1 Jan 2004
Giaretti Walter, Molinu Silvia, Ceccarelli Jenny, Prevosto Claudia
Abstract excerpt
Whether in vivo specific gene mutations lead to chromosomal instability (CIN) and aneuploidy or viceversa is so far not proven. We hypothesized that aneuploidy among human sporadic colorectal adenomas and KRAS2 and APC mutations were not independent. Additionally, we investigated if 1p34-36 delet...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
