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Article

The role of CKIP-1 in cell morphology depends on its interaction with actin-capping protein.

The Journal of biological chemistry - 24 Nov 2006

Canton David A, Olsten Mary Ellen K, Niederstrasser Hanspeter, Cooper John A, Litchfield David W

Abstract excerpt

CKIP-1 is a pleckstrin homology domain-containing protein that induces alterations of the actin cytoskeleton and cell morphology when expressed in human osteosarcoma cells. CKIP-1 interacts with the heterodimeric actin-capping protein in cells, so we postulated that this interaction was responsible for the observed cytoskeletal and morphological effects of CKIP-1. To test this postulate, we used peptide "walking...

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Identifiers

PMID: 16987810
DOI: 10.1074/jbc.M607595200
PMCID: PMC2583070

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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