Phenotype of preneoplastic and neoplastic liver lesions during spontaneous liver carcinogenesis of LEC rats.

doi:10.1093/carcin/11.10.1857

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Article

Phenotype of preneoplastic and neoplastic liver lesions during spontaneous liver carcinogenesis of LEC rats.

Carcinogenesis - 1 Oct 1990

Sawaki M, Enomoto K, Takahashi H, Nakajima Y, Mori M

Abstract excerpt

The incidence and phenotype of preneoplastic and neoplastic liver lesions appearing in LEC rats after recovery from severe hereditary hepatitis were studied in comparison with the liver lesions appearing in chemical liver carcinogenesis. The livers of 168 rats (90 male, 78 female) were stained for seven histochemical markers at different time periods from the 20th week to the 122nd week of life....

Topics

Adenosine Triphosphatases
Aging
Animals
Carboxylesterase
Carboxylic Ester Hydrolases
Female
Glucose-6-Phosphatase
Glutathione Transferase
Isoenzymes
Liver
Liver Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Phenotype

Precancerous Conditions

Rats

Rats, Inbred Strains

alpha-Fetoproteins

gamma-Glutamyltransferase

Source

Open in PubMed

Identifiers

PMID: 1698569
DOI: 10.1093/carcin/11.10.1857

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1698569-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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