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Article

Enzyme and immunohistochemical phenotyping of diethylnitrosamine-induced liver lesions of male C3H/He, B6C3F1 and C57BL/6J mice.

Carcinogenesis - 1 Apr 1992

Buchmann A, Bock K W, Schwarz M

Abstract excerpt

Male C3H/He, B6C3F1 and C57BL/6J mice were given a single injection of diethylnitrosamine (20 micrograms/g body wt) on day 15 after birth and animals were killed 17-29 (C3H/He and B6C3F1) and 29-46 weeks (C57BL/6J) after treatment. Carcinogen-induced liver lesions were identified by a deficiency in the marker enzyme glucose-6-phosphatase and the enzymatic phenotypes of these lesions were studied by enzyme and...

Topics

Animals
Cytochrome P-450 Enzyme System
Diethylnitrosamine
Immunohistochemistry
Isoenzymes
Liver
Liver Neoplasms, Experimental
Male
Mice
Mice, Inbred C3H
Mice, Inbred C57BL

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Identifiers

PMID: 1576719
DOI: 10.1093/carcin/13.4.691

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1576719-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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