Article
Ultrastructural appearances of preneoplastic liver nodules induced through sequential treatment in rats.
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer - 1 Jan 2000
Pesce C, Grillo-Ruggieri F, Maura A L
Abstract excerpt
The ultrastructural appearances of preneoplastic liver nodules induced in male Wistar rats through sequential treatment with diethylnitrosamine (DENA) and 2-acetylaminofluorene (2-AAF) followed by partial hepatectomy were investigated. Although separately non-specific, the lesions reported repres...
Topics
- 2-Acetylaminofluorene
- Animals
- Cocarcinogenesis
- Diethylnitrosamine
- Hepatectomy
- Liver Neoplasms
- Male
- Methods
- Microscopy, Electron
- Phenotype
- Precancerous Conditions
- Rats
- Rats, Inbred Strains
