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Article

Number of simultaneously expressed enzyme alterations correlates with progression of N-ethyl-N-hydroxyethylnitrosamine-induced hepatocarcinogenesis in rats.

Japanese journal of cancer research : Gann - 1 Dec 1993

Yamaguchi S, Hakoi K, Ozaki K, Kato T, Tiwawech D, Nagao S, Takahashi H, Matsumoto K, Tsuda H

Abstract excerpt

Preneoplastic and neoplastic liver cell lesions, induced by EHEN (N-ethyl-N-hydroxyethylnitrosamine) in rats, were investigated to establish the numbers of simultaneously expressed altered enzyme phenotypes within the lesion cells. The lesions were divided into 5 classes on the basis of altered expression in one or more of the following 5 enzymes: glutathione S-transferase placental form, glucose-6-phosphate...

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Identifiers

PMID: 7904986
DOI: 10.1111/j.1349-7006.1993.tb02828.x
PMCID: PMC5919116

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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